Interview coming up - how do I handle recurring medical appointment?

you should seriously try to get the medical appointment scheduled on weekends or after/before the work day. It is going to be very difficult to either get a job offer if you disclose this during the interview or if you don't disclose it, get the employer to agree to your conditions once you are hired. However if there is no way you can reschedule the appointments, I would disclose this at the interview - it would be better if you are hired that the employer already knows of the time restriction rather than to get the job and spring it on them once you are working.